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BioWeapon Hepatitis-C 5x times more deadly then Hep-B - no vaccine


Scientist says Hepatitis C is 5 time more deadly then Hep B. And what is Hepatitis D?

Ask why - Merck pushed Hepatitis B vaccine on newborns? - Vaccine Schedule 1983 vs. 2008

See the whole thread: Aflatoxin - Hepatitis B - Liver Cancer - Genetic Warfare - Eugenics

http://www.taipeitimes.com/News/taiwan/archives/2009/06/18/2003446487
Hepatitis C raises risk of liver cancer, expert warns

CAUTION: Michael Lai of the Academia Sinica said that risks are high given the lack of a vaccine for hepatitis C, with medication only effective in 50 percent of cases
By Meggie Lu STAFF REPORTER
Thursday, Jun 18, 2009, Page 2

Contrary to previous findings, people with hepatitis C are five times as likely to develop liver cancer as those with hepatitis B, a leading researcher said yesterday.

Speaking at the 12th Society of Chinese Bioscientists in America (SCBA) International Symposium, Michael Lai (賴明詔), vice president of Academia Sinica, said that combined with heavy drinking, the risk level rises to 10 times.

Lai made the statement during the presentation of his latest paper, "A journey through RNA viruses: From coronavirus to hepatitis C virus replication and pathogenesis."

Nicknamed “the father of coronavirus,” Lai yesterday also received the SCBA Lifetime Achievement Award, the highest SCBA honor.

Hepatitis is a common illness of the liver, which affects millions of people in Asia. While the prevalence of hepatitis C in Taiwan is 2 percent, it is higher for hepatitis B.

“There are hepatitis A, B, C, D and E; While hepatitis A and E are acute, B, C and D are chronic liver diseases,” said Lai, who is also the president of National Cheng Kung University.

In the past, up to 90 percent of the nation's liver cancer cases were caused by hepatitis B, but this has been reversed since the development of the hepatitis B vaccine, he said.

“In southern Taiwan, more than half of liver cancer cases are induced by hepatitis C,” Lai said.

“Because the disease does not yet have a vaccine and medication is also only effective in 50 percent of cases, it is very important that we work on developing a hepatitis C vaccine,” he said.

Lai added that the probability of hepatitis C patients getting liver cancer was much higher than those with hepatitis B.

“While the amount of time that the hepatitis C virus is found in the human body is usually shorter — because whereas most hepatitis B patients contract the virus in early childhood, many hepatitis C patients get the disease later in life — those with hepatitis C are five times as likely as their counterparts to develop liver cancer,” he said.

The risks of people with hepatitis C contracting liver cancer could rise another two-fold — or 10 times more than the risk level for people with hepatitis B — if they are heavy drinkers or consume a large amount of high-fat foods, Lai said.

Hepatitis C sufferers should therefore abstain from alcohol and engage in routine liver function checks every four months, he said.

“Many people in the south go to local pharmacies to receive 'nutrient injections,' an effort to give their livers supplements,” Lai said. “However, this kind of behavior may only make their conditions worse,” he said.


Rose Medical Center tech may have infected patients
http://www.denverpost.com/breakingnews/ci_12745889?source=rss
By Joey Bunch The Denver Post Updated: 07/02/2009 10:00:48 PM MDT


A Rose Medical Center operating room technician, who was fired after failing a drug test for a powerful pain medication, potentially infected thousands of patients with hepatitis C, hospital officials and federal prosecutors said tonight.

Hospital officials said they knew the technician had the virus when she was hired. [LIHOP? MIHOP?] She began work on Oct. 21, 2008. She was fired on April 13.

Rose is offering free testing to all people who had surgery in the main hospital or the Wolf Building between those dates. Letters will be sent to more than 4,700 former patients. Maternity and emergency room patients are not affected.

Hospital officials stressed at a Thursday night news conference that the employee is not confirmed to be the source of the infection and the Colorado Health Department is continuing its investigation.

Hospital officials would not identify the technician, but court papers obtained by the Gazette newspaper in Colorado Springs identified her as Kristen Diane Parker, 26, of Colorado Springs. She is in federal custody.

Quoting paperwork on the charges obtained from a Department of Justice official, the Gazette said charges against Parker were filed by the U.S. Attorney's office in Denver on Thursday.

A spokesman for the U.S. Attorney's office did not return telephone calls Thursday night.

In a videotaped interview with police on Monday, according to the Gazette, Parker told a detective she used heroin from July to September last year.

She allegedly told the investigator she thought she caught the virus from injecting herself with dirty needles.

Rose Hospital officials said the state health department had found nine former Rose patients who tested positive for hepatitis C.

Parker also might have exposed 1,000 patients at Audubon Ambulatory Surgery Center in Colorado Springs, where she worked after being fired from Rose, according to the charges against her.

The complaint states Parker admitted exchanging dirty syringes she had injected herself with and then filled with saline for syringes filled with more fentanyl.

Fentanyl is a powerful narcotic pain medication given to surgery patients.

Parker allegedly injected the narcotic at home or in the hospital bathrooms, according to the Gazette.

Jeff Dorsey, the president and chief executive of HealthOne, which operates Rose and other hospitals, said he was angered by the surgery technician's breach of trust.

"Someone in this particular case violated the trust everyone has, and that we value," he said at an evening press conference at the hospital.

Hepatitis C is a contagious liver disease. The Centers for Disease Control and Prevention estimates more than 8,000 people a year die from hepatitis C-related liver disease.

Hepatitis C can be treated and cured. Most people have no symptoms.

Dorsey said the technician's behavior led to the drug test that caused her to be fired immediately. The firing took place before the state health department contacted the hospital about the possible infections.

Former patients should receive their letter on Tuesday or Wednesday at the latest, Dorsey said. The hospital also has created a phone line for those concerned, 303-329-7500. The line will be staffed from 7 a.m. to 7 p.m. beginning Monday. Dorsey asked that patients wait on a letter before calling.

According the Gazette, Parker told a Denver police investigator in the videotaped interview, "I know I (expletive) up. I can't take back what I did, but I will have to live with it for the rest of my life, and so does everybody else."

She told the investigator she expected to spend the rest of her life in prison.

On her MySpace page, Parker said she is the mother of a young son. She states that she has "a crazy fascination with needles."

Among the artwork on the page is the figure of a man driven full of nails beneath the word and definition of, "Guilt ... the fact of having done a wrong, especially an act punishable by law."

On June 1, a former surgical nurse at Boulder Community Hospital in Boulder pleaded guilty in federal court to stealing large amounts of a fentanyl for his own use, while refilling the vials with water. [looks like a common trend to increase exposure to Hep C, hire heroin addicts with Hep C and you get a larger testbed of lab mice to work with]

Ashton Daigle, 27, struck a plea deal that will result in a minimum sentence of 54 months in prison when he is sentenced on Oct. 26.

Daigle said he sprayed the drug into his nose.


Quote
[looks like a common trend to increase exposure to Hep C, hire heroin addicts with Hep C and you get a larger testbed of lab mice to work with

Exactly!

Hepatitis C outbreak springs from Endoscopy Center of Nevada; 40,000 at risk
February 27, 2008


http://www.yourlawyer.com/topics/overview/Endoscopy_Center
The Endoscopy Center of Southern Nevada routinely reused syringes on multiple patients, a negligent practice which exposed thousands of patients to blood borne diseases, including Hepatitis C, Hepatitis B and HIV, the virus that causes AIDS.

That last article stated:
Quote
Hepatitis C can be treated and cured.


That's not true! You can't be "cured" of Hepatitis C

http://www.dbs.nus.edu.sg/eventlist/seminars/poster/2002/michael%20lai.pdf

Michael M. C. Lai, M.D., PhD
Distinguished Professor, Dept. of Molecular Microbiology and Immunology, Howard Hughes Medical Institute Investigator, University of Southern California, USA
Deputy Director of Academia Sinica, Taipeh.

Professor Lai, a world renowned expert on coronavirus, will present current knowledge on
the molecular biology of SARS coronavirus, its gene structure, organisation, evolution and
replication. He will also highlight the various strategies for vaccine and therapeutics to combat
SARS.

Quote
Professor Lai: “Because the disease does not yet have a vaccine and medication is also only effective in 50 percent of cases, it is very important that we work on developing a hepatitis C vaccine,” he said.

http://www.ias.ac.in/currsci/oct252006/996a.pdf
Origin of hepatitis C virus
...
Additionally,  the possibility of HCV being a bio-warfare agent cannot be ruled out completely.
C. D. PODURI Department of Biotechnology/ Bioinformatics,

Aflatoxin - Hepatitis B - Liver Cancer - Genetic Warfare - Eugenics

Have you ever heard of Typhoid Mary?  Well, Here is a Hepatitis C - Typhoid Mary:

infectious silent chronic HCV carriers:  How many were there?
Note that this woman had no reason to have HCV, yet had it. The HCV infection she had put off NO anti-bodies that could be used to screen her blood. She donates blood for years and the recipents come down with HCV.

http://www.ncbi.nlm.nih.gov/pubmed/10919211

Discovery of a chronic HVC infection without seroconversion in a blood donor in France during 28 months

ETS Bretagne, Rennes, France.

The HCV-RNA screening technique developed by the French Fractionation and Biotechnology Laboratory singled out in March 1998 a case of positive HCV-RNA viremia in a blood donor without any anti-HCV antibody.

That donor was a 46-year-old woman who had made 54 donations of blood products from 1988 to 1997. She had no history of blood transfusion, no history of hepatitis and no life-style risk factor.

Clinical examination was normal. Liver tests (serum alanine amino transferases, gamma glutamyl transpeptidase , alkaline phosphatase, bilirubin , prothrombin and albumin) were normal. Total blood count was normal. Lymphocyte count was normal as well as in vitro functional analysis of lymphocytes (stimulation with different antigens).

All screening HCV Elisa tests and immunoblot System available on the French market were unable to detect anti-HCV antibodies. Quantification of serum HCV-RNA (Amplicor Monitor Roche) showed 294,000 copies/mL and HCV genotype 1b determination was performed using Innolipa assay.

Further examination of the HCV genotype by direct sequencing of the PCR product showed a classical 1b genotype sequence. The hemovigilance inquiry identified 25 labile products distributed since 1988.

Analyzing the records of the recipients that have so far been traced and identified revealed three periods: 1997 to 1995: three recipients were found to be positive for anti-HCV antibodies; two are now cured of hepatitis C. In one recipient, direct sequencing after specific PCR of the hypervariable region coding for the envelope domain showed 100% homology with the donor;

1993 to 1990: four recipients were identified and traced without contamination; in 1988: three of four blood product recipients were anti-HCV negative without HCV-RNA viremia. The forth carried anti-HCV antibodies and genotype 1b HCV-RNA but had a history of multiple surgery. Alter et al. [4] and Bush et al. [5] have previously suggested the possibility of a chronic, immunologically silent state of infection.

The case described herein, is the first evidence for this hypothesis. Indeed, the donor has not yet seroconverted 28 months after viremia was discovered. This blood donor was identified by HCV-RNA screening of plasma products. The identification of the same sequence in a recipient of blood from this donor clearly establishes the transmission of the virus by transfusion.

The prevalence of such cases of infectious silent chronic HCV carriers has to be determined and the mechanisms responsible for the absence of antibody production need to be clarified.


Even the CDC admits there are people getting this for no apparent reason:

http://www.cdc.gov/mmWR/PDF/rr/rr4719.pdf
Recommendations for Prevention and Control of Hepatitis C Virus (HCV)
Infection and HCV-Related Chronic Disease

...
Persons with No Recognized Source for Their Infection.
...
 Thus, a potential risk factor can be identified for approximately 90% of persons with HCV infection.
In the remaining 10%, no recognized source of infection can be identified, although most persons in this category are associated with low socioeconomic level. Although low socioeconomic level has been associated with several infectious diseases and might be a surrogate for high-risk exposures, its nonspecific nature makes targeting prevention measures difficult.


And G whiz Rockefeller U. and the Gates Foundation is heavy into HCV research and creating NEW strains of HCV:

 http://newswire.rockefeller.edu/index.php?page=engine&id=491
Posted: March 27, 2006
 
Researchers show laboratory hepatitis C strain is also infectious in animal models

An important step in developing a treatment for viral diseases is for scientists to culture live viruses from infected patients, but the hepatitis C virus (HCV), a major cause of chronic and sometimes fatal liver disease, has proven to be particularly wily.

For many years scientists have struggled with an inability to efficiently culture HCV in the laboratory.

 Now, researchers at Rockefeller University have overcome several obstacles and successfully shown that a strain of HCV they created in the laboratory, which can efficiently be cultured in vitro, is also infectious in animals. The findings, reported in the March 7 issue of the Proceedings of the National Academy of Sciences, will enable scientists to study the life cycle of HCV at the molecular level and develop better treatments for this disease.
 
The researchers, led by Brett Lindenbach at Rockefeller and Philip Meuleman at Ghent University in Belgium, used a cell-culture version of HCV, developed by Lindenbach and colleagues at Rockefeller, called HCVcc. HCVcc, which was the first infectious cell-culture version of hepatitis C, was used to infect two chimpanzees as well as mice bearing human liver grafts. The researchers found that in both the chimpanzees and the mice, hepatitis C infection lasted for as long as 15 weeks. Also, the infections raised in the mice could be passed to other mice. Samples of the test tube-cultured strain could be recovered from infected animals and was easily recultured in vitro, unlike most other strains of HCV isolated from infected animals or people.

“The ability to study a genetically defined virus in the test tube and in living animals allows us to completely dissect the HCV life cycle,” says senior author Charles Rice, Maurice R. and Corinne P. Greenberg Professor and head of the Laboratory of Virology and Infectious Disease at Rockefeller.
...

http://www.rockefeller.edu/research/abstract.php?id=143
Heads of Laboratories Charles M. Rice, Ph.D.
Maurice R. and Corinne P. Greenberg Professor
Laboratory of Virology and Infectious Disease
E-mail: ricec@rockefeller.edu
...
A major roadblock in HCV antiviral development and vaccine research is establishing a small animal model where HCV replication, immunogenicity and pathogenesis can be studied. The Rice lab is working with an international consortium, funded by a Gates Foundation Grand Challenges grant, on methods to implant human liver cells and immune cells in mice. Success in creating such an animal model for HCV will have broad implications for developing vaccines for HIV, malaria and other uniquely human pathogens
...


So we have Bio-weapons diseases developed by the military and distributed by the blood banks, Bayer Corporation, Baxter Corporation and American Red Cross etc...

They give the early 1948 date for HCV but it sounds like "backdating" the disease to me.


Must read:
http://www.hcvets.com/data/transmission_methods/vaccine_contamination.htm

Hepatitis C Origin 
http://www.hcvets.com/data/transmission_methods/published_articles/studies.htm#Hepatitis C Origin

Points to Possible Military Link Copyright 1999 by Forward Times- DOCUMENTS RAISE QUESTIONS ABOUT VIETNAM ERA EXPERIMENTS ED WENDT-Documents obtained by Forward Times under the Freedom of Information Act, for an investigation of the hepatitis C epidemic, reveal that U.S. servicemen were used to test experimental vaccines while they were in Basic Combat Training during the Vietnam Era
“ blood samples of American servicemen taken in 1948 were recently reviewed during a study. Those samples detected the hepatitis C virus.”

http://nationalhepatitiscinstitute.org/Data/Transmission/ISGContamination.htm

Baxter Agrees to Settle Hepatitis C Claims Related to Use of Immune Globulin

WESTPORT, Dec 22 2000 (Reuters Health) - Baxter Healthcare has agreed to the terms of a proposed class action settlement brought by individuals who contracted or were exposed to hepatitis C virus through use of Baxter's immune globulin therapy, Gammagard, between January 1, 1993 and February 24, 1994.

Financial terms of the settlement were not disclosed by Baxter or the plaintiffs' class counsel.  However, the Deerfield, Illinois medical products firm said that members of the class would receive financial compensation.

Baxter voluntarily withdrew the immune-boosting product from the market in February 1994 after receiving reports from more than 200 patients who claimed that they were infected with hepatitis C virus after using Gammagard.

In the November 1996 issue of the Journal of the American Medical Association, Dr. Joseph S. Bresee of the US Centers for Disease Control and Prevention and colleagues reported on a study of nearly 300 patients who received immune globulin between March 1993 and February 1994.  As reported by Reuters Health, the researchers found that 11% of the patients who received Gammagard had contracted hepatitis C virus compared with none who received other products exclusively.

In may 1994 Baxter launched Gammagard S/D, whose manufacture includes an additional processing step that inactivates viruses such as hepatitis C.  There have been no reports of hepatitis C virus associated with Gammagard S/D, according to the company.

According to terms of the proposed settlement, patients who received Gammagard during the class action period could receive free test to determine whether they  have contracted hepatitis C virus.  Those who are infected with the virus are eligible to receive payments based on progression of the illness.  Those who did not contract the virus are also eligible for payment, according to Baxter.

John Evans of Specter, Specter, Evans & Manogue, the Pittsburgh, Pennsylvania-based lead counsel for the plaintiff class, said that the settlement "...was designed with individual patients' needs in mind, providing financial relief based on specific medical symptoms of hepatitis C they may exhibit today or in the future."

Baxter noted that the estimated cost of the settlement will be covered by previously established financial reserves.  The settlement must receive approval from the judge overseeing the class action

Immune Globulin IVIG

Immune Globulin intravenous IVIG is a protein found in the plasma component of blood.  Plasma is collected and pooled by domestic fractionators such as Bayer Corporation, Baxter Corporation and American Red Cross.  Igiv is prepared as a sterile solution, contains no preservatives and is treated to prevent transmitting viruses.  The U.S. Food and Drug Administration regulates its preparation, distribution and use.

Immune globulin is used to treat primary immunodeficiency's. It is especially useful when high levels or elevation of circulating antibodies are desired.  Immune globulin comes in sterile solution or lyophilized powder and is administered intravenously. 


The CDC  has continually  downplayed High risk activities to HCV transmission.

Quote
Tattoos, piercing, acupuncture and personal grooming items have never transmitted HIV, but are high risk routes for HCV transmission.
The Veterans Affairs grants HCV service connection for tattoos received during service, toothbrushes, razors, and inoculations from unsafe injections


http://hcvets.com/PublicHealth/Report.htm#_edn20

Reactionary Response
    
To this day, scientists and advocates alike are concerned that political, rather than science based influence within public health policies has caused a divide to exist.  Neal Lane, former Science Advisor to the President and former Director of the National Science Foundation stresses how Industry groups are fighting government regulation by fomenting scientific uncertainty," "...with the help of irresponsible members of Congress and other public officials, corporate greed can trump any sense of ethics, morality, and human compassion.” [9]

Over the last 8 years, CDC funding has declined 65% with an equivalent reduction in their capacity to function. The impact on infectious diseases in the USA has radically changed, and our health priorities are now short term reactionary responses as substitute for long term prevention, which significantly lowers the cumulative costs of chronic disease and health care.

The CDC/HIV Hepatitis disease prevention plan for HCV is a prime example of the short term reactionary response and its failure to protect the public.  The plan segregates methods for HCV transmission into "high risk" groups and targets education and prevention campaigns in such a way it causes stigma. The "high risk" groups are legally defined in the HIV Ryan White Care Act which stipulates all disease grant funding resources must address HIV risk factor "only"; this, despite the fact HCV is much more infectious.

Tattoos, piercing, acupuncture and personal grooming items have never transmitted HIV, but are high risk routes for HCV transmission. The Veterans Affairs grants HCV service connection for tattoos received during service, toothbrushes, razors, and inoculations from unsafe injections. To date, the CDC has not warned the general public to these dangers; a whole segment of society are ignored while HIV campaigns focus HCV transmission on the least likely, if at all possible, mode of transmission, sex. [10]
...
Society in Jeopardy
As a result, the largest public health patient notification in the history of the USA occurred this year, FY 2008.
Public health sent in excess of 70,000, letters warning of possible HCV exposure from unsafe medical practices involving several clinics.[11]  Following a joint investigation with the Nevada State Bureau of Licensure and Certification (BLC) and with consultation from the CDC, identified the re-use of syringes (not needles) and the use of single dose vials of anesthesia medication on multiple patients, as the potential sources of contamination.

The Southern Nevada Health District reported that 200 people are testing positive daily in public health departments. [12]  Ironically, the head of the CDC, Julia Louise Gerberding says; "The outbreak of HCV may represent the tip of an iceberg” of safety problems at clinics around the country". [13]

After similar outbreaks in New York, the FDA has rejected that state's request to ban multidose vials[14], saying the vials are critical in hospital use. [15]  The CDC says, "Use all vials labeled as "single-use" for one patient and entered one time only". "Assign medications packaged as multidose to a single patient whenever possible." [16]

Multidose vials fail in comparison to the impertinence for standard procedures. The World Health Organization states, "The only means of protection from the Hepatitis C virus are the implementation universal precautions and safe injection practices." Nation-wide, from 2004-2008, tens of thousand medical exposures to HCV have occurred with an undetermined number of positive infections because of policy differences. Medical exposures surpass any other risk factor for HCV infections.[17]

The Military banned large multidose vials in 1998 and in theory, plays a role in the high rate of HCV among US Troops that served during the peak of the HCV epidemic. One in 5 retired military and Vietnam veterans have HCV [18]

http://www.sciencenews.org/view/generic/id/43337/title/New_weapon_fights_hepatitis_C

New weapon fights hepatitis C
Experimental drug clears hurdle on its way to joining standard drug combinations
By Nathan Seppa
May 23rd, 2009; Vol.175 #11 (p. 12)

Ten years ago, John McHutchison never used the word “cure” when discussing hepatitis C with his patients. But the results seen from drugs cleared for use since then — and particularly a new drug now in the final stages of testing — are changing that, says the gastroenterologist from Duke University in Durham, N.C.

“As far as these patients are concerned, they’re pretty much cured,” McHutchison says. “We don’t need to see them anymore.”

The new drug, called telaprevir, works with a standard hepatitis C drug combination to clear the virus from patients’ blood substantially better than the standard treatment alone, according to a study coauthored by McHutchison and another study, both in the April 30 New England Journal of Medicine. The new findings, in people getting their first course of drugs for the disease caused by the virus, also indicate that typically lengthy hepatitis C treatment could be halved with telaprevir’s addition.

Telaprevir appears to be a material advance in the therapy of hepatitis C, beginning a new era of treatment,” says physician Jay Hoofnagle of the National Institute of Diabetes and Digestive and Kidney Diseases in Bethesda, Md., writing in an editorial in the same NEJM issue. Unlike existing hepatitis drugs, telaprevir is a protease inhibitor.

A third study finds that about half of people who hadn’t responded to initial treatment for hepatitis C or had relapsed cleared the virus after getting the combination including telaprevir. Those data were presented April 25 in Copenhagen at a meeting of the European Association for the Study of the Liver.

In general, patients are considered cured if they don’t have detectable hepatitis C virus for six months after drug treatment. More than 99 percent of such patients continue to stay free of the virus for the next five years, says Jean-Michel Pawlotsky, a hepatologist at the Henri Mondor Hospital in Créteil, France, and coauthor of the other study in NEJM.

The researchers agree that the drug can cure many of those patients who have received treatment but were still fighting a losing battle with hepatitis C.

“We had to tell them we had nothing to offer,” Pawlotsky says. “Now there might be something to offer.”


McHutchison and his colleagues randomly assigned 250 hepatitis C patients to get the standard drugs ribavirin and peginterferon alfa-2a, with or without telaprevir. The team found that 61 to 67 percent of those getting telaprevir were cured, compared with 41 percent of those not getting it.

Pawlotsky and his colleagues looked at 334 patients in Europe. The cure rates ranged from 60 to 69 percent with telaprevir compared with 46 percent with ribavirin and peginterferon alfa-2a alone, Pawlotsky says.

Both studies in NEJM found that taking telaprevir for three months and the standard drugs for five and a half months worked as well as taking the standard drugs for the usual 11-month course.

In the study reported at the Copenhagen meeting, 453 patients who had failed to respond to earlier treatment or had relapsed afterward were similarly assigned to get telaprevir or not as part of a combination. Hepatologist Michael Manns of the Hannover Medical School in Germany and his colleagues reported that slightly more than half of those getting telaprevir were cured, compared with only 14 percent of those getting just standard drugs.

The studies were funded by Vertex Pharmaceuticals of Cambridge, Mass., which makes telaprevir. Schering-Plough also makes a protease inhibitor, called boceprevir, which tested well against first-time–treated hepatitis C patients, according to other researchers presenting data at the Copenhagen meeting.

About 3.2 million people in the United States have hepatitis C. It infects about 180 million people worldwide. Hepatitis C can cause fatigue, fever, jaundice and abdominal pain. Patients who fail to improve during treatment or who relapse afterward risk developing cirrhosis of the liver and liver cancer. The virus comes in four varieties. In these studies, all patients had genotype 1, the most common and difficult-to-treat kind in Europe and North America.

Both telaprevir and boceprevir are currently in large-scale trials now. McHutchison says he expects both to get approved, possibly as early as 2011.


Hemopurifier - Another treatment is to filter the blood... Baxter has one of these too....

So these blood companies put HCV into the blood and now they are going to filter it out. Great.

Oh bio-filter's = Battelle

http://www.accessmylibrary.com/coms2/summary_0286-37480300_ITM
AETHLON HEMOPURIFIER ADJUNCT THERAPY FOR HEPATITIS-C.
Publication Date: 01-MAY-09

COPYRIGHT 2009 Worldwide Videotex

Aethlon Medical, Inc. (OTC Bulletin Board: AEMD), San Diego, has announced clinical data that supports the advancement of the Aethlon Hemopurifier(R) as an adjunct therapy to increase Hepatitis-C (HCV) cure rates. The Hemopurifier(R) is a first-in-class medical device that assists the immune response in combating infectious disease through real-time therapeutic filtration of infectious viruses and immunosuppressive proteins. In HCV care, the device inhibits viral replication through selective elimination of HCV in circulation and assists to preserve immune cells by removing toxic proteins shed from the surface of HCV.

Aethlon disclosed that data resulting from over 20 HCV treatments indicates an average viral load reduction of 41% during each four-hour Hemopurifier(R) treatment.

In the studies, average pre-treatment viral load of 22,868,000 HCV virus copies/ml blood (cpm) was reduced on average by 9,300,000 cpm during the course of each treatment. Based on this data, Aethlon predicts that short-term continuous Hemopurifier(R) treatment can reduce viral load to low to undetectable levels, thus improving the likelihood that HCV patients achieve a sustained virological response (SVR) from the current interferon-ribavirin standard of care and other candidate therapies.

HCV infection is considered cured when SVR extends beyond six months. At present, less than 50% of HCV patients respond to interferon-ribavirin therapy. Additionally, there is a direct correlation between low viral load at onset of interferon-ribavirin therapy and increased cure rates. Based on data analyzed from each four-hour Hemopurifier(R) treatment, Aethlon projects that a patient with a high viral load of 7 million iu/ml would be reduced to undetectable HCV levels after approximately three days of continuous Hemopurifier(R) treatment.

This corresponds to a 4.06 log reduction or an 11,000-fold decrease in viral load. An HCV patient with a moderate viral load of 2 million iu/ml would be projected to reach undetectable levels in approximately 2.5 days of continuous treatment. All of the studies were conducted in highly health compromised HCV infected patients who suffer from end-stage renal disease (ESRD) requiring regular kidney dialysis treatment. In these treatment studies, the Hemopurifier(R) inhibited the progression of HCV infection in ESRD patients when included during dialysis treatment administered thrice weekly for four-hours. The studies were conducted at the Fortis Hospital in Delhi, India.

About Hepatitis-C Virus

HCV is a leading cause of chronic liver disease and liver transplants. The World Health Organization (WHO) estimates that nearly 180 million people worldwide, or approximately 3% of the world's population, are infected with HCV.

130 million of these individuals are chronic HCV carriers who are at increased risk of developing liver cirrhosis or liver cancer, approximately 15 million of whom are in the United States, Europe and Japan.

The CDC has reported that almost four million people in the United States have been infected with HCV, of whom 2.7 million were chronically infected. Approximately 2.6%, or 71,000, of these HCV patients are treated each year. Although chronic HCV infection varies greatly in its course and outcomes, 70% of chronically infected patients develop some form of chronic liver disease, including, in some cases, cirrhosis or liver cancer.

In the United States, the current standard of care for the treatment of HCV is a combination of pegylated interferon and a nucleoside analog named ribavirin. According to WHO, treatment with interferon in combination with ribavirin is effective in 30% to 50% of patients, while interferon alone is effective in approximately 10% to 20% of patients.

In HCV genotypes 1a and 1b, which account for over 70% of HCV infections in the US, less than 50% of these patients respond to standard therapy consisting of pegylated interferon plus ribavirin.

In addition, these therapies have serious side effects that include fatigue, bone marrow suppression, anemia and neuropsychiatric effects. As a result of the limited benefits and serious side effects of existing therapies, significant value is placed on promising antiviral strategies to fight HCV. The Aethlon Hemopurifier(R) is positioned to improve the benefit of the current interferon-ribavirin standard of care, as well as other candidate HCV drug therapies demonstrating promise in clinical studies.

About Aethlon Medical

Aethlon Medical creates diagnostic and therapeutic filtration devices to improve the health of individuals afflicted with infectious disease and cancer. Aethlon's lead product, the Hemopurifier(R), is a first-in-class artificial adjunct to the immune system proven to capture infectious viruses and immunosuppressive particles from the human circulatory system.

The device targets to inhibit disease progression of Hepatitis-C Virus (HCV) and Human Immunodeficiency Virus (HIV), and serves as a broad-spectrum treatment countermeasure against bioterror and emerging pandemic threats.

The Hemopurifier(R) also holds promise in cancer care, as research studies verify the Hemopurifier(R) effectively captures immunosuppressive exosomes that are secreted by tumors to kill-off immune cells. At present, over sixty-five (65) Hemopurifier(R) treatments (representing approximately 260 hours of treatment time) have been conducted in multi-site studies at the Apollo Hospital, Fortis Hospital, and Sigma New-Life Hospital in India. The studies enrolled end-stage renal disease (ESRD) patients infected with either HCV or HIV. In addition to establishing treatment safety, robust viral load reductions have been reported in both HCV and HIV infected individuals.

Research studies have also demonstrated the Hemopurifier(R) is effective in capturing a broad-spectrum of viruses untreatable with drug therapy, including several of world's deadliest bioterror and pandemic threats.

These include: Dengue hemorrhagic fever (DHF), Ebola hemorrhagic fever (EHF), Lassa hemorrhagic fever (LHF), H5N1 avian influenza (Bird Flu), the reconstructed 1918 influenza virus (r1918), West Nile virus (WNV), and Vaccinia and Monkeypox (MPV), which both serve as models for human smallpox infection.

The studies were conducted with the assistance of researchers representing: The U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID); The Centers for Disease Control and Prevention (CDC); The National Institute of Virology (NIV); The Battelle Biomedical Research Center (BBRC); and The Southwest Foundation for Biomedical Research (SFBR).

Beyond therapeutic market opportunities, Aethlon is leveraging principles underlying the Hemopurifier(R) technology platform to establish a pipeline of clinical and research diagnostic products and services.

For more information, visit http://www.aethlonmedical.com/ or call 858/459-7800, ext. 303.


Hep C is a silent killer epedemic.... you did read the TyphoidMary Hep-C-Mary post above?

http://www.prn.org/index.php/coinfections/article/acute_hepatitis_c_infection_433
Therapeutic Implications of Acute Hepatitis C Infection
Elmar Jaeckel, MD
Department of Cancer Immunology and AIDS
Dana-Farber Cancer Institute
Boston, Massachusetts

The hepatitis C virus's greatest weapon might very well be its silence. It is an infection that is initially asymptomatic and often goes unrecognized, anywhere from several years to more than two decades after the infection has established itself in the liver. Because of this, countless individuals in this country and elsewhere are not aware that they are, in fact, chronically infected with the virus.

This is also true during the acute stage of infection. While symptoms such as fatigue, lethargy, myalgia, low-grade fever, nausea and vomiting do occur in patients with acute HCV infection, they are virtually indistinguishable from more common and benign viral infections and, as a result, usually go unchecked.

Even one of HCV's hallmark features-jaundice-develops in fewer than half of all individuals during acute infection, even though HCV-RNA and liver enzyme levels are usually at their highest.
....
[author goes on to say how great interferon is....]


Eugenics Business Model:

Exactly  - they hit up to 2-3% of the world population with Global-Genocide penetration and then start bringing out the "cures" which they make more money on. Rinse and repeat.

It's so sick... and added bonus, the "cure" makes you suicidal...

Interferon makes you suicidal
Treatment with interferon is strongly associated with severe depression, suicidal ideation, and suicide attempts.


Hybrid Dengue Fever virus with Hepatitis C developed in 2001!

"Vaccine Research"  - mosquito delivery system?
90 percent of Dengue fever is misdiagnosed in the U.S.
50 percent of HCV infections are asymptomatic - ie people think they have the flu
173.5 million Americans and. 5.2 billion people (global) could be infected with a "emerging" new and novel virus via mosquitoes


State of the art Mosquito Research Facility (MRF) in Cairns Funded by Gates Foundation

resistant strain of Marlaria in China $23 million from the Bill & Melinda Gates Foundation

Bill Gates Unleashes Swarm of Mosquitoes on Crowd

The Bill and Melinda Gates Foundation awarded 100,000 dollars each on Wednesday to scientists in 22 countries including funding for a Japanese proposal to turn mosquitos into "flying syringes" delivering vaccines.


See: Climate change could boost U.S. dengue fever - HCV BioWeapon

http://www.i-sis.org.uk/GMbioWeapons.php

Quote
In August 2001, Imperial College of London University was prosecuted and ordered to pay £65 000 in fines and legal fees for exposing the public to a deadly new hybrid of the dengue fever virus and gene sequences associated with hepatitis C.

http://www.sciencemag.org/cgi/content/summary/293/5531/779b
Science 3 August 2001:

GENETIC ENGINEERING:
Imperial College Fined Over Hybrid Virus Risk
John Pickrell
HERTFORDSHIRE, U.K.--One of the United Kingdom's top research institutes has been ordered to pay almost $65,000 in fines and legal fees for risking the release of a potentially deadly hybrid virus. Government inspectors had charged Imperial College, London, with failure to follow health and safety rules in a study that involved the creation of a chimera of the hepatitis C and dengue fever viruses, both of which cause severe illness. On 23 July, a crown court judge upheld the charges and found the college guilty of failing to adequately protect laboratory workers and the public.

http://www.guardian.co.uk/uk/2001/jul/24/highereducation.education
College fined for risky virus work

Imperial College, one of Britain's leading research institutions, was fined £25,000 yesterday for exposing staff to possible infection from a hybrid virus for which there is no known cure.

It was also ordered to pay more than £21,000 in prosecution costs at Blackfriars crown court, south London, after being accused of a "seriously flawed" approach to health and safety matters.

The court heard that there was a possibility that the hybrid hepatitis C and dengue fever virus could have been released into the air. Ventilation procedures were inadequate, no protection equipment was available in the event of a spillage, and there was no proper system for waste disposal.

Keith Morton, prosecuting, said: "The prosecution say that while this was important work, that can be no excuse for the failures revealed. Hepatitis C causes severe infection and is frequently fatal, but is difficult to catch, whereas dengue fever can cause severe but rarely dangerous infection, but is severely infectious.

"However, a hybrid virus was unpredictable. Its tropism, the tissue in which it would reproduce, was unpredictable, and there was no vaccine or treatment."

The prosecution said the college showed disregard for safety measures. Employees were exposed to "a very real risk of infection, aggravated by the fact that safety advice _ was ignored".

The breaches occurred amid growing concern in the college about general standards of safety at its St Mary's hospital campus in Kensington, west London, where the work was done. The research was intended to speed up the search for a hepatitis C vaccine.

Imperial College admitted one count of "failing to apply principles of good microbiological practices and of good occupational safety and hygiene" under regulations controlling the use of genetically modified organisms. It also pleaded guilty to breaching health and safety law.

---------------
Why is this important. Because Dengue Fever is spread by Mosquitos, so they could also spread other diseases (like Hep-C HCV) along with the Dengue Fever:

http://in.reuters.com/article/environmentNews/idINTRE5676M820090708
Climate change could boost U.S. dengue fever cases
Thu Jul 9, 2009
By Deborah Zabarenko, Environment Correspondent

WASHINGTON (Reuters) - Climate change could push dengue fever into all corners of the United States, as the mosquitoes that can carry the traditionally tropical virus survive warmer U.S. winters, researchers said on Wednesday.

Known colloquially as breakbone fever for the aching bones that are one symptom of the disease, dengue fever can be treated effectively with bed rest and liquids, but it often goes undiagnosed in the United States.

Two species of mosquitoes capable of transmitting dengue fever have been spotted in 28 states and Washington D.C., according to a report by the Natural Resources Defense Council. Cases of the disease have been reported in every U.S. state, but many of those are so-called imported cases where the patient was infected by mosquitoes elsewhere in the world.

Dengue fever, a long-standing problem in tropical areas, was until recently rare in most of the United States, except along the Texas-Mexico border. That could be changing due to a range of factors including global warming, scientists at the Natural Resources Defense Council said in a report.

As few as 10 percent of U.S. dengue infections are correctly diagnosed, Kim Knowlton, one of the report's authors, said by telephone.

"Because there has been, up to this point, the perception that it's a tropical concern, we think it's not been on the radar of many clinicians," she said.

"Rising temperatures do affect the range of these two mosquito vectors, to the extent that warming winter temperatures can allow mosquitoes to overwinter more successfully and therefore be able to survive in new parts of the country," Knowlton said.

Nearly 4,000 cases of imported and locally transmitted dengue fever were reported in the United States by the Centers for Disease Control and Prevention between 1995 and 2005; if cases along the Texas-Mexico border area are included, that number rises to 10,000.

As temperatures rise, the potential for transmission may increase in vulnerable parts of the United States, as warmer temperatures and changing rainfall conditions expand both the area suitable for the mosquito vectors and the length of the transmission season," the report said.

About 173.5 million U.S. residents live in counties with one or both of the mosquito species that can transmit dengue fever, according to the report.

Worldwide, dengue fever and its complications cause 50 to 100 million infections and 22,000 deaths annually in more than 100 countries.

By 2085, an estimated 5.2 billion people are projected to be at risk for dengue due to rising temperatures and humidity spurred by climate change, the report said.

More information is available online at www.nrdc.org/health/dengue/  (Editing by Cynthia Osterman)

Kidney Dialysis Machines spreading HCV (in China):

http://www.upi.com/Health_News/2010/01/06/Hospital-reports-hepatitis-C-outbreak/UPI-75841262802517/
Hospital reports hepatitis C outbreak
Published: Jan. 6, 2010 at 1:28 PM

ANQING CITY, China, Jan. 6 (UPI) -- Fifteen kidney dialysis patients were infected with hepatitis C at a hospital in China's Anhui Province, authorities said.

The patients were infected at Yicheng Hospital, said health officials, who opened an investigation last month after several patients with renal issues were diagnosed with the disease.

Thirty-nine of 77 dialysis patients treated at the hospital were found to have hepatitis C, but only 15 cases could be linked to the hospital's dialysis clinic, Xinhua, China's state-run news agency, reported Wednesday.

"There's a chance that some of the patients may have had the disease before taking the dialysis treatment," an unidentified health official told Xinhua.

Patients confirmed to have contracted hepatitis at the hospital would receive free treatment, the spokesman said.

In America:
http://medical-malpractice.lawyers.com/blogs/archives/928-Hepatitis-C-Outbreak-at-Atlantic-City-Hospital.html

Hepatitis C Outbreak at Atlantic City Hospital
Tuesday, May 5, 2009 by Joseph L. Messa
Officials at have reported 15 cases of hepatitis C at AtlantiCare Regional Medical Center in Atlantic City, New Jersey.  Administrators from the AtlantiCare Regional Medical Center’s City Campus contacted the state this month after discovering five recent cases of hepatitis C during an annual federally mandated hepatitis C testing of dialysis patients.

Testing took place in April as well as early this month.  Five patients became positive for hepatitis C since they began undergoing treatment at AtlantiCare. Reports state that the 15 patients contracted the serious and sometimes deadly liver disease starting in 2005.

According to New Jersey health officials, the state saw over 100 acute and 7,000 chronic hepatitis C cases in 2007, adding that the Center’s dialysis unit treats between 70 to 80 kidney patients monthly, with patients visiting the center three times a week for dialysis. Kidney dialysis involves the patient’s blood being pumped into a dialysis machine, where it is filtered and returned to the patient’s body. Dialysis machines at the center are inspected once every two years. The hospital maintains it follows strict guidelines that include disinfection and cleaning of the equipment.

The 15 infected patients were part of a group of 245 patients.  The dialysis center has a lower-than-average patient survival rate when compared to the state. The origin of the virus is still unknown.  Patricia Diamond, Atlantic County Health Officer, said finding the source of the virus might not be easy.  “Any investigation of a communicable disease is not black and white.  They are complicated. All of the information has to be carefully reviewed before anything is determined.”  Improper maintenance or use of dialysis machines is medical malpractice.

The hospital, the state, and health officials are diligently working to determine the cause and origin of the virus.

HVC spreading in Hospitals:

http://www.attorneyatlaw.com/2010/01/judge-rejects-plea-deal-for-hepatitis-c-hospital-tech/
http://www.attorneyatlaw.com/2009/09/former-surgical-tech-admits-infecting-patients-with-hepatitis-c/

Former Surgical Tech Admits Infecting Patients With Hepatitis C
A former Colorado surgical technician has pleaded guilty to federal charges she stole pain drugs then shared the dirty needles with patients, exposing thousands of people to a risk of Hepatitis C.

Kristen D. Parker, who also worked at hospitals in New York and Texas, pleaded guilty to charges of tampering with a consumer product and obtaining a controlled substance by deceit. She now faces a 20-year prison sentence when she is formally sentenced, according to a New York Times report.

Parker fed her addiction to pain-killing drugs by taking medications set aside for surgical patients, injecting the drugs into herself, then filling the syringes with saline solution and returning them to surgical trays for later use on patients.

States Investigate Possible Infections
At least 27 patients at Rose Medical Center in Denver and Audubon Surgery Center in Colorado Springs, where Parker worked from October 21, 2008 until July 6, 2009, have tested positive for the serious blood disorder that can permanently affect liver functioning, officials said.

Officials also warned thousands of other patients at Northern Westchester Hospital Mount Kisco, New York and Christus St. John Hospital near Houston, where Parker worked before moving to Colorado. It is unclear how many patients may have been exposed to dirty needles at those facilities, but officials sent warning letters to more than 6,000 people who underwent surgical procedures during Parker’s stints there.

Parker was arrested over the summer, indicted on more than 40 federal charges, and faced a possible life prison term if convicted. However, she agreed to plead guilty and in exchange for that cooperation now faces a maximum term of 20 years, officials said.

http://www.attorneyatlaw.com/2009/07/hospital-worker-arrested-accused-of-exposing-thousands-to-hepatitis-c/
Hospital Worker Arrested, Accused of Exposing Thousands to Hepatitis C

As many as 6,000 patients who underwent surgery at a Denver-area hospital over a six-month period are being advised to have a blood test to determine whether they were exposed to hepatitis C by a hospital worker.

Kristen Diane Parker, a 26-year-old surgical scrub nurse at Rose Medical Center, has been accused of using syringes filled with painkillers meant for patients on herself, then refilling the syringes with saline solution. Parker allegedly was addicted to painkillers and was feeding her addiction by stealing the drugs intended for use in surgical patients. By reusing the needles she used to inject herself on patients, officials say Parker exposed thousands of patients to hepatitis C.